James Hamilton, M. D.
Folks,
Since we have gotten back a little on the COVID-19 pandemic I would like to bring up a few things that I have been pondering now for some time. And I do not write this with any political bias.
On several prior posts and personal e-mails I have mentioned that this virus, SARS-CoV-2, is the most unusual one that I have seen in my lifetime. It is very easily transmittable from human to human yet certain populations are more and others much less, susceptible to its severe disease states. It seeks out cells of almost every organ in the body to which it attaches. That fact seems a bit obvious to me since ACE-2 receptors - to which the virus spike protein attaches allowing it to enter cells - are widespread throughout many organs in the body plus being on the lining of arteries and arterioles. Some of the mutations of the virus ("variants") are even more contagious than the original and some of those may also be more fatal. The current vaccines differ in their ability to handle the different variants and more research needs to be done on that topic.
As more cases accumulate among those who survived the initial infection, researchers are finding that lots of organ systems have long term effects (?damage?). Whether these are permanent is as yet unknown.
It has long been known that some diseases are capable of being transferred to humans from animals. Coronaviruses seem to fit that category. Originally the prevailing thoughts were that this virus was transmitted from bats and pangolins to man via inhalation or ingestion, through a wet market in Wuhan, China. There seems to be ever increasing evidence now that the virus came from the Wuhan Institute of Virology (WIV), just a short distance from that wet market. Was this virus accidentally released or was it intentionally released? Was the wet market actually a source, a bystander or not involved at all? These are just some of the questions being considered.
The WIV was doing "gain of function" research on viruses. That type of research is very dangerous and questionable in the minds of many. In the best of hands the idea is to engineer a virus that is more virulent and study how to prevent/treat it. Is SARS-CoV-2 such a virus? Some scientists believe it is or, at least, could be.
Back to what I said before: this is the most unusual virus that I have ever seen in my lifetime. Could such a virus have occurred naturally and could it have transitioned from bats to man so quickly, or was it an engineered virus? This lab is said to have the highest of security available. Yet some of their workers had reportedly become sick. There are also many cages of bats being kept inside that lab.
Granted, I am no virology expert. But there are others who are and are thinking along these lines.
If a foreign power wanted to develop a bioweapon to use - not acutely, but rather over a period of time - against its rivals, this would be an effective one.
The world needs answers.
Jim
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